http://www.fda.gov/AboutFDA/WhatWeDo/History/Origin/ucm054819.htm. Due to sodium benzoate's preservative and antifungal properties, it is often used in conventional and even some green cleaning furniture polishes, toilet bowl cleaners, dishwashing detergent gels, carpet cleaning products, upholstery cleaners, and dishwasher cleaners. The primary mechanism of action for benzoates is believed to be a function of their acid dissociation quotient (pKa). 44. It is most widely used in acidic foods such as salad dressings (i.e. If the pH inside the cell falls to 5 or lower, the anaerobic fermentation of glucose through an enzyme called phosphofructokinase decreases sharply. The Food and Drug Administration (FDA) includes Benzoic Acid and Sodium Benzoate on its list of direct food substances affirmed as Generally Recognized As Safe ().Benzyl Alcohol and Benzyl Benzoate are also approved as a synthetic flavoring agents for direct addition to food. Sodium benzoate has been used to cover or enhance the scent of products and also as an anticorrosive. Cautions: While Sodium Benzoate is typically good for all skin types, in extreme cases it may cause skin rash or irritation, rash, hives, and swelling. acetic acid in vinegar), carbonated drinks (carbonic acid), jams and fruit juices (citric acid), pickles (acetic acid), condiments, and frogurt toppings. Enns GM, Berry SA, Berry GT, Rhead WJ, Brusilow SW, Hamosh A. Appleton H, Simmons W. The Handbook of Soap Manufacture. %PDF-1.5 Ascorbic Acid. It is the sodium salt of benzoic acid and exists in this form when dissolved in water. J Am Acad Dermatol. I don’t think it is many formulators favourite though, because there are other preservatives that work better. New York, NY: Springer; 2005:331-350. Food intolerance causes a slower reaction than a true food allergy. Hausen B. Sodium benzoate is a synthetic additive and preservative made by combining benzoic acid and sodium hydroxide. Sodium benzoate is a preservative that crops up on ingredient lists for skin care products. J Inherit Metab Dis. . The Gutenberg Project. The Dermatologist. Benzoates are primarily used today as preservatives, especially in consumable and personal hygiene products. 9. Nijhawen RI, Matiz C, Jacob SE. Militello G, Jacob SE, Crawford GH. He’s still famous, not for his science but for some confusing predictions he made that continue to be talked about. Archives of Disease in Childhood; The Effects of a Double Blind, Placebo Controlled, Artificial Food Colourings and Benzoate Preservative Challenge on Hyperactivity in a General Population of Preschool Children; B. Bateman, et al. BENZOIC ACID, SODIUM SALT, SODIUM BENZOATE, and SODIUM SALT BENZOIC ACID. Food Safety and Inspection Service. 2016:33(2):213-215. Arch Dis Child. In skincare, it helps prevent corrosion and sometimes even save the metallic-material packages from rusting. Disclosure: Dr McGowan reports no relevant financial relationships. Summary Sodium benzoate medicine can be used to treat high blood ammonia levels. 4. Antoine L. Elements of Chemistry. Read more here. March 12, 2013. http://www.courthousenews.com/2013/03/12/55664.htm. 2006;18(4):385-390. Sodium benzoate is the sodium salt of benzoic acid and is commonly used as an antimicrobial substance and food preservative. It is also being studied for potential use in other conditions, including schizophrenia and multiple sclerosis.  - Antoine Lavoisier, Elements of Chemistry, 17896, Alchemist Michel de Nostradame, more popularly known as prophesier Nostradamus, first described benzoic acid in 1556.7,8 To produce benzoic acid, Nostradame dry-distilled gum benzoin, the balsam resin from trees of the genus Styrax.9 (“Gum” is a misnomer, as resin is not a water-soluble polysaccharide.9) Gum benzoin was popularly used at that time in fragrances, especially incense.10 Other benzoates were discovered and used as fragrances and flavorings. 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